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Impact of Allergic Response

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IMMEDIATE TYPE I RESPONSE: NATURAL RUBBER LATEX ALLERGY

A latex Type I response is a reaction to residual proteins found in natural rubber latex.4 The reaction is immediate, typically occurring 5–30 minutes after initial contact. The symptoms are commonly:

  • Swelling and redness, local to the site of exposure
  • Non-specific symptoms such as itching and burning

The symptoms can spread to areas remote to the site of contact with the glove, and can be accompanied by:

  • Conjunctivitis
  • Rhinitis
  • Bronchial obstruction

In rare cases, symptoms of anaphylaxis can occur.


A NURSE'S STORY: LIVING WITH A LATEX ALLERGY




DELAYED TYPE IV RESPONSE: DELAYED OR ALLERGIC CONTACT DERMATITIS

A chemical Type IV allergy is a reaction to specific allergens such as chemical residues from the glove manufacturing process (commonly known as chemical accelerators). The response is delayed rather than immediate, usually occurring 6- 48 hours after initial contact, although symptoms can last for up to 4 days. The symptoms include:

  • Erythema
  • Swelling
  • Cracking
  • Itching
  • Weeping
  • Dryness of the skin at the site (dermatitis may extend beyond the area of contact)

Delayed or allergic contact dermatitis possibly has an itchy rash comprising scaling, redness and blisters




A closer view of the redness and blisters signalling a Type IV allergic response

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